SUBCUTANEOUS REACTION OF RABBITS TO HORSE SERUM
نویسندگان
چکیده
منابع مشابه
Subcutaneous Reaction of Rabbits to Horse Serum
1. Anaphylaxis or allergy of rabbits against horse serum can be proved by subcutaneous test. 2. The test is best made in the following way. The skin of the animal, preferably of the abdomen or flank, is shaved. (This should be done a few hours before the injection.) The injection is made by means of a small hypodermic syringe and intradermally. An effort was made not to inject the serum under t...
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1. Normal rabbits in the course of their development, after infancy, vary in their responses to minute doses of horse serum given intracutaneously. 2. There is increased reactivity in males as they mature, beginning, in the stock employed in these experiments, at about the age of 13 weeks when a weight of 1,700 gm. has been attained. 3. The reactivity of normal females remains at a constant lev...
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1. Rabbits which have received a single dose of normal horse serum in the subarachnoid space produce precipitins in the blood in greater abundance, of higher titer, and persisting longer than those in control rabbits which have received a similar injection intravenously. 2. Repeated subarachnoid injections of normal horse serum in rabbits induce precipitins in the blood early. These may appear ...
متن کاملFurther Observations on Anaphylaxis to Horse Serum
In a previous paper (I) on the reaction of the guinea-pig to single and repeated doses of horse serum, I took the view that the violent reaction obtained at a second treatment which follows the first after a considerable incubation period, was due to the participation in the reaction of a specific reaction product or anti-body developed by the animal during the interval. In support of this posi...
متن کاملThe Effects of Various Horse Serum Fractions in Producing Cardiovascular and Renal Lesions in Rabbits
Five groups of 10 rabbits each were injected intravenously 2 times at 15 day intervals with either whole horse serum or one of its cold alcohol-precipitated fractions. Suitable serological and general observations were made at appropriate intervals before and after each injection. All animals were sacrificed on the 22nd day of the experiment. A study of the antemortem and pathological findings ...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1910
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.12.4.562